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Development of the Korean Version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K)

Clinical and Neuropsychological Assessment Batteries

^a Department of Neuropsychiatry, Kangwon National University Hospital, Chunchon, Kangwon-do, Korea
^b Neuroscience Research Institute, Medical Research Center, Seoul National University, Seoul, Korea
^c Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
^d Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea
^e Douglas Fellow in Medical Informatics, Center for Clinical Computing, Harvard Medical School, Boston, Massachusetts
^f Department of Business Administration, Seogang University, Seoul, Korea
^g Department of Psychiatry, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
^h Department of Neurology, Chungbuk National University, College of Medicine, and Chungbuk National University Hospital, Chungchongbuk-do, Korea

Jong I. Woo, Department of Neuropsychiatry, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul, Korea (110-744) E-mail: jiwoomd{at}plaza.snu.ac.kr.

Decision Editor: Toni C. Antonucci, PhD

A Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K) was created. The English-American version of CERAD clinical and neuropsychological assessment batteries was translated into Korean, and the psychometrical properties of the cognitive tests in the CERAD-K were established. In the translation, including back-translation, the basic structures of all measures in the original CERAD batteries were maintained. The CERAD-K was administered in a standardized manner to 106 dementia patients (aged 70.4 ± 8.1 years), including 78 Alzheimer's disease (AD) patients, and 186 controls (aged 68.4 ± 4.6 years) who were recruited from 3 university hospitals and 2 elderly welfare centers. The cognitive tests in the CERAD-K successfully differentiated controls from the dementia patients and from the AD patients. They also showed substantial interrater reliability and 1-month test-retest reliability. The CERAD-K is an equally reliable and valid equivalent for the English version of the CERAD clinical and neuropsychological assessment batteries.